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Choukèr, Alexander; Kaufmann, Ines; Kreth, Simone; Hauer, Daniela; Feuerecker, Matthias; Thieme, Detlef; Vogeser, Michael; Thiel, Manfred and Schelling, Gustav (21. May 2010): Motion sickness, stress and the endocannabinoid system.
In: PLOS ONE 5(5), e10752 [PDF, 338kB]


A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel. Motion sickness can be extremely stressful but the neurobiologic mechanisms leading to motion sickness are not clear. The endocannabinoid system (ECS) represents an important neuromodulator of stress and N&V. Inhibitory effects of the ECS on N&V are mediated by endocannabinoid-receptor activation.

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