Pearson, David; Hienzsch, Antje; Wagner, Mirko; Globisch, Daniel; Reiter, Veronika; Özden, Dilek; Carell, Thomas
LC-MS based quantification of 2’-ribosylated nucleosides Ar(p) and Gr(p) in tRNA.
In: Chemical communications, Vol. 47: pp. 5196-5198
RNA nucleosides are often naturally modified into complex non-canonical structures with key biological functions. Here we report LC-MS quantification of the Ar(p) and Gr(p)
2'-ribosylated nucleosides in tRNA using deuterium labelled standards, and the first detection of Gr(p) in complex fungi.