Borasio, Gian Domenico
Carbamazepine-responsive paroxysmal nausea and vomiting in a patient with meningeal carcinomatosis.
In: Palliative Medicine, Vol. 20, No. 5: pp. 549-550
In neurology, paroxysmal syndromes are well-known, eg, as manifestations of multiple sclerosis. We report a patient with meningeal carcinomatosis, who presented with therapyrefractory nausea and vomiting. The clinical suspicion of a paroxysmal syndrome prompted a trial of carbamazepine, which resulted in complete cessation of the symptoms. In cancer patients with central nervous system (CNS) involvement and therapy-refractory symptoms with sudden onset, carbamazepine treatment should be considered.