The aza-Morita-Baylis-Hillman reaction of electronically and sterically deactivated substrates.

Lindner, Christoph; Tandon, Raman; Liu, Yinghao; Maryasin, Boris and Zipse, Hendrik (2012): The aza-Morita-Baylis-Hillman reaction of electronically and sterically deactivated substrates. In: Organic and Biomolecular Chemistry, Vol. 10, No. 16: pp. 3210-3218

Abstract

The aza-Morita–Baylis–Hillman (azaMBH) reaction has been studied for electronically and sterically deactivated Michael acceptors. It is found that electronically deactivated systems can be converted with electron-rich phosphanes and pyridines as catalysts equally well. For sterically deactivated systems clearly better catalytic turnover can be achieved with pyridine catalysts. This is in accordance with the calculated affinities of the catalysts towards different Michael-acceptors.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Chemistry and Pharmacy
• Subjects: 500 Science > 540 Chemistry
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: English