Statics and dynamics of single DNA molecules confined in nanochannels

Reisner, Walter; Morton, Keith .J; Riehn, Robert; Wang, Yan Mei; Yu, Zhaoning; Rosen, Michael; Sturm, James C.; Chou, Stephen Y.; Frey, Erwin and Austin, Robert H. (May 2005): Statics and dynamics of single DNA molecules confined in nanochannels. In: Physical Review Letters, Vol. 94, No. 19: pp. 196101-1

Abstract

The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Physics
• Subjects: 500 Science > 530 Physics
• ISSN: 0031-9007
• Place of Publication: ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA
• Language: English