Aktuelle Entwicklungen und Perspektiven zielgerichteter Therapien

Dickgreber, Nicolas; Huber, Rudolf M.; Reck, Martin; Reinmuth, Niels; Schütte, Wolfgang; Serke, Monika and Wolf, Jürgen (2010): Aktuelle Entwicklungen und Perspektiven zielgerichteter Therapien. In: Onkologie, No. 5: pp. 2-11

Abstract

Current Developments and Perspectives in Targeted Therapies Many different approaches for improving the prognosis of patients with advanced non-small-cell lung cancer (NSCLC) are currently being investigated. This article discusses the significance of maintenance therapy after primary chemotherapy and reviews study data on second-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), inhibitors of insulin-like growth factor receptors (IGFR), vascular-disrupting agents (VDAs) and multi-TKIs of vascular endothelial growth factor receptors (VEGFR). The article also looks at the future prospects of using genetic markers in the field of NSCLC.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 0378-584X
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: German