A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

Lundwall, A.; Band, V.; Blaber, M.; Clements, J A; Courty, Y.; Diamandis, E P; Fritz, H.; Liija, H.; Malm, J.; Maltais, L J; Olsson, A Y; Petraki, C.; Scorilas, A.; Sotiropoulou, G.; Stenman, Ulf-Hakan; Stephan, C.; Talieri, M. und Yousef, G M (2006): A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. In: Biological Chemistry, Bd. 387, Nr. 6: S. 637-641

Abstract

The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

• Dokumententyp: Zeitschriftenartikel
• Publikationsform: Publisher's Version
• Fakultät: Medizin
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1431-6730
• Allianz-/Nationallizenz: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
• Sprache: Englisch