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Braun, Andreas; Deufel, Thomas; Geilenkeuser, Wolf-Jochen; Neumaier, Michael; Röhle, Gerhard; Roscher, Adelbert; Wagener, Christoph (1998): External quality assessment of molecular biology-based methods used in laboratories of clinical chemistry and human genetics. In: Clinical Chemistry and Laboratory Medicine, Vol. 36, No. 4: pp. 231-234




The Reference Institute of Bioanalysis of the German Society of Clinical Chemistry has performed the first external assessment of molecular genetics methods used in medical diagnosis. The following procedures were tested: (I) DNA preparation from whole blood, (II) PCR amplification using "standard" primers, and (III) submarine agarose gel electrophoresis. Out of 50 participants, 45 returned samples for evaluation.