Diagnostic and prognostic impact of desmocollins in human lung cancer

Cui, Tiantian; Chen, Yuan; Yang, Linlin; Mireskandari, Masoud; Knösel, Thomas; Zhang, Qing; Kohler, Lukas Herbert; Kunze, Almut; Presselt, Norbert; Petersen, Iver (December 2012): Diagnostic and prognostic impact of desmocollins in human lung cancer. In: Journal of clinical pathology, Vol. 65, No. 12: pp. 1100-1106

Abstract

Desmosomes are intercellular junctions that confer strong cell-cell adhesion. Two main members of desmosomal cadherins, desmogleins (DSGs) and desmocollins (DSCs), are involved in carcinogenesis. However, their role in human lung cancer remained elusive. The aims of this study were to analyse the expression of DSCs and to evaluate their clinical application in lung cancer.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1472-4146
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: English