TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients

Koumakis, Eugénie; Wipff, Julien; Dieudé, Philippe; Ruiz, Barbara; Bouaziz, Matthieu; Revillod, Lucile; Guedj, Mickaël; Distler, Jörg H. W.; Matucci-Cerinic, Marco; Humbert, Marc; Riemekasten, Gabriella; Airo, Paolo; Melchers, Inga; Hachulla, Eric; Cusi, Daniele; Wichmann, Heinz-Erich; Hunzelmann, Nicolas; Tiev, Kiet; Caramaschi, Paola; Diot, Elisabeth; Kowal-Bielecka, Otylia; Cuomo, Giovanna; Walker, Ulrich; Czirják, László; Damjanov, Nemanja; Lupoli, Sara; Conti, Costanza; Müller-Nurasyid, Martina; Müller-Ladner, Ulf; Riccieri, Valeria; Cracowski, Jean-Luc; Cozzi, Franco; Bournia, Vasiliki Kalliopi; Vlachoyiannopoulos, P.; Chiocchia, Gilles; Boileau, Catherine und Allanore, Yannick (November 2012): TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients. In: Annals of the rheumatic diseases, Bd. 71, Nr. 11: S. 1900-1903

Abstract

Systemic sclerosis (SSc)-related pulmonary arterial hypertension (PAH) has emerged as a major mortality prognostic factor. Mutations of transforming growth factor beta (TGFβ) receptor genes strongly contribute to idiopathic and familial PAH.

• Dokumententyp: Zeitschriftenartikel
• Publikationsform: Publisher's Version
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1468-2060
• Allianz-/Nationallizenz: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
• Sprache: Englisch