First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study

Holzapfel, Christina; Grallert, Harald; Baumert, Jens; Thorand, Barbara; Döring, Angela; Wichmann, Heinz-Erich; Hauner, Hans; Illig, Thomas and Mielck, Andreas (February 2011): First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study. In: Journal of epidemiology and community health, Vol. 65, No. 2: pp. 174-176

Abstract

Strong evidence exists for an association between socioeconomic status and body mass index (BMI) as well as between genetic variants and BMI. The association of genetic variants with socioeconomic status has not yet been investigated. The aim of this study was to investigate two obesity-related loci--the transmembrane 18 (TMEM18) and the fat mass and obesity-associated (FTO) gene--for their association with educational level and per capita income, and to test whether the detected genotype-BMI association is mediated by these social factors.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1470-2738
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: English