MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease

Schormair, Barbara; Plag, Jens; Kaffe, Maria; Gross, Nadine; Czamara, Darina; Samtleben, Walter; Lichtner, Peter; Ströhle, Andreas; Stefanidis, Ioannis; Vainas, Andreas; Dardiotis, Efthimios; Sakkas, George K.; Gieger, Christian; Müller-Myhsok, Bertram; Meitinger, Thomas; Heemann, Uwe; Hadjigeorgiou, Georgios M.; Oexle, Konrad and Winkelmann, Juliane (July 2011): MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease. In: Journal of medical genetics, Vol. 48, No. 7: pp. 462-466

Abstract

Restless legs syndrome (RLS) is a sleep related movement disorder that occurs both in an idiopathic form and in symptomatic varieties. RLS is a frequent and distressing comorbidity in end stage renal disease (ESRD). For idiopathic RLS (iRLS), genetic risk factors have been identified, but their role in RLS in ESRD has not been investigated yet. Therefore, a case-control association study of these variants in ESRD patients was performed.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1468-6244
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: English