Bell, Nicholas A. W.; Thacker, Vivek V.; Hernandez-Ainsa, Silvia; Fuentes-Perez, Maria E.; Moreno-Herrero, Fernando; Liedl, Tim; Keyser, Ulrich F.
(12. March 2013):
Multiplexed ionic current sensing with glass nanopores.
In: Lab on a Chip, Vol. 13, No. 10: pp. 1859-1862
We report a method for simultaneous ionic current measurements of single molecules across up to 16 solid state nanopore channels. Each device, costing less than $20, contains 16 glass nanopores made by laser assisted capillary pulling. We demonstrate simultaneous multichannel detection of double stranded DNA and trapping of DNA origami nanostructures to form hybrid nanopores.