Next-generation personalized drug discovery: the tripeptide GHK hits center stage in chronic obstructive pulmonary disease

Meiners, Silke and Eickelberg, Oliver (2012): Next-generation personalized drug discovery: the tripeptide GHK hits center stage in chronic obstructive pulmonary disease. In: Genome Medicine 4:70

Abstract

Chronic lung diseases (CLDs), including chronic obstructive pulmonary disease (COPD), are the second leading cause of death worldwide. The first report of database-driven drug discovery in carefully phenotyped COPD specimens has now been published in Genome Medicine, combining gene expression data in defined emphysematous areas with connectivity-map-based compound discovery. This joint effort may lead the way to novel and potentially more efficient concepts of personalized drug discovery for COPD in particular, and CLD in general.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1756-994X
• Language: English