
Abstract
A versatile visual approach for detecting recombination and identifying recombination breakpoints within a sequence alignment is presented. The method is based on two novel diagrams - the highway plot and the occupancy plot - that graphically portray phylogenetic inhomogeneity along an alignment, and can be viewed as a synthesis of two widely used but unrelated methods: bootscanning and quartet-mapping. To illustrate the method, simulated data and HIV-1 and influenza A datasets are investigated.
Item Type: | Journal article |
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Form of publication: | Publisher's Version |
Faculties: | Mathematics, Computer Science and Statistics > Statistics |
Subjects: | 500 Science > 570 Life sciences; biology |
URN: | urn:nbn:de:bvb:19-epub-23801-3 |
ISSN: | 1465-6914 |
Language: | English |
Item ID: | 23801 |
Date Deposited: | 06. Mar 2015, 11:21 |
Last Modified: | 04. Nov 2020, 13:05 |