Bender, A.; Scheipl, F.; Küchenhoff, H.
Modeling Exposure-Lag-Response Associations with Penalized Piece-wise Exponential Models.
Department of Statistics: Technical Reports, Nr. 192
We present a novel approach for the flexible modeling of exposure-lag-response associations, i.e., time-to-event data where multiple past exposures are cumulatively associated with the hazard after a certain temporal delay. Our method is based on piece-wise exponential models and allows estimation of a wide variety of effects, including potentially smooth and time-varying effects as well as cumulative effects with leads and lags, taking advantage of the advanced inference methods that have recently been developed for generalized additive mixed models.
Alle Versionen dieses Dokumentes
Modeling Exposure-Lag-Response Associations with Penalized Piece-wise Exponential Models. (deposited 09. Mrz. 2016 19:07)