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Möckl, L.; Müller, A.; Bräuchle, Christoph und Lindhorst, T. K. (2016): Switching first contact: photocontrol of E. coli adhesion to human cells. In: Chemical Communications, Bd. 52, Nr. 6: S. 1254-1257 [PDF, 1MB]

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Abstract

We have shown previously that carbohydrate-specific bacterial adhesion to a non-physiological surface can be photocontrolled by reversible E/Z isomerisation using azobenzene-functionalised sugars. Here, this approach is applied to the surface of human cells. We show not only that bacterial adhesion to the azobenzene glycoside-modified cell surface is higher in the E than in the Z state, but add data about the specific modulation of the effect.

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