Switching first contact: photocontrol of E. coli adhesion to human cells

Möckl, L.; Müller, A.; Bräuchle, Christoph and Lindhorst, T. K. (2016): Switching first contact: photocontrol of E. coli adhesion to human cells. In: Chemical Communications, Vol. 52, No. 6: pp. 1254-1257

Abstract

We have shown previously that carbohydrate-specific bacterial adhesion to a non-physiological surface can be photocontrolled by reversible E/Z isomerisation using azobenzene-functionalised sugars. Here, this approach is applied to the surface of human cells. We show not only that bacterial adhesion to the azobenzene glycoside-modified cell surface is higher in the E than in the Z state, but add data about the specific modulation of the effect.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Chemistry and Pharmacy
• Subjects: 500 Science > 540 Chemistry
• ISSN: 1359-7345
• Annotation: First published online 19 Nov 2015
• Language: English