Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms

Huber, Tatjana; Weisheit, Lara und Magauer, Thomas (2015): Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms. In: Beilstein Journal of Organic Chemistry, Bd. 11: S. 2521-2539

Abstract

This review describes strategies for the chemical synthesis of xenicane diterpenoids and structurally related metabolites. Selected members from the four different subclasses of the Xenia diterpenoid family, the xenicins, xeniolides, xeniaphyllanes and xeniaethers, are presented. The synthetic strategies are discussed with an emphasis on the individual key reactions for the construction of the uncommon nine-membered carbocycle which is the characteristic structural feature of these natural products. Additionally, the putative biosynthetic pathway of xenicanes is illustrated.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Chemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1860-5397
• Sprache: Englisch