Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms

Huber, Tatjana; Weisheit, Lara and Magauer, Thomas (2015): Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms. In: Beilstein Journal of Organic Chemistry, Vol. 11: pp. 2521-2539

Abstract

This review describes strategies for the chemical synthesis of xenicane diterpenoids and structurally related metabolites. Selected members from the four different subclasses of the Xenia diterpenoid family, the xenicins, xeniolides, xeniaphyllanes and xeniaethers, are presented. The synthetic strategies are discussed with an emphasis on the individual key reactions for the construction of the uncommon nine-membered carbocycle which is the characteristic structural feature of these natural products. Additionally, the putative biosynthetic pathway of xenicanes is illustrated.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 1860-5397
• Language: English