Synthesis of polyfunctional secondary amines by the addition of functionalized zinc reagents to nitrosoarenes

Dhayalan, Vasudevan; Sämann, Christoph und Knochel, Paul (2015): Synthesis of polyfunctional secondary amines by the addition of functionalized zinc reagents to nitrosoarenes. In: Chemical Communications, Vol. 51, No. 15: pp. 3239-3242

Abstract

Addition of functionalized aryl, heteroaryl or adamantyl zinc reagents to various nitroso-arenes in the presence of magnesium salts and LiCl in THF produces after a reductive work-up with FeCl2 and NaBH4 in ethanol the corresponding polyfunctional secondary amines in high yields.

• Item Type: Journal article
• Form of publication: Publisher's Version
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 1359-7345
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Annotation: First published online 09 Jan 2015
• Language: English