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Schultz, Gernot; Soll, Jürgen and Ellerbrock, Bernd H. (1981): Site of Prenylation Reaction in Synthesis of Phylloquinone (Vitamin K1) by Spinach Chloroplasts. In: European Journal of Biochemistry, Vol. 117, No. 2: pp. 329-332 [PDF, 406kB]


In spinach chloroplasts, 1,4-dihydroxy-2-naphthoate is prenylated by phytyldiphosphate and subsequently methylated by S-adenosylmethionine to form phylloquinol. The site of the prenylation reaction is the chloroplast envelope membrane.

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