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Denk, Nora; Fritsche, Jens; Reese, Sven ORCID: 0000-0002-4605-9791 (2011): The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. In: Veterinary ophthalmology, Vol. 14, No. 3: pp. 186-194
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Objective: To evaluate the effect of UV-blocking soft contact lenses in treatment for chronic superficial keratitus (CSK). Methods: Twenty six dogs with CSK were treated continuously with UV-blocking contact lenses for 6 months. A contact lens was placed on one eye ofeach dog; the other eye remained without a lens as a control eye. After ö.-kthis primary study, five of the dogs were further treated and they worethen contact lenses in both eyes. Continuously, all patients wereconcurrently treated topically with cyclosporine. The contact lenseswere changed every 4 weeks and an ophthalmic examination performed.Evaluation criteria included corneal alterations as pigmentation, edema,pannus and vascularization. To determine the transmittancecharacteristics of the contact lenses before and after use, 32 contactlenses were measured with a UV-vis-NIR spectrophotometer.ResultsPigmentation increased in eyes wearing lenses and in control eyes overthe evaluation period of 6 months. Corneal edema increased in the eyeswearing lenses, but remained unaffected in the control eyes. A significant difference in the incidence of pannus and the extent ofcorneal vascularisation could not be evaluated. Adverse effects werenoted in six cases (corneal edema and vascularisation, conjunctivitis,blepharospasm). All new lenses studied reduced UV-radiation to a safelevel, whereas used lenses did not maintain their transmittancecharacteristics. Conclusions: No positive effect of UV-blocking contact lenses could be proven withthe study design used.