Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans

Rüffer, Martina und Zenk, Meinhart H. (1987): Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans. In: Tetrahedron Letters, Bd. 28, Nr. 44: S. 5307-5310

Abstract

A microsomal cytochrome P-450-NADPH dependent enzyme which hydroxylates stereo- and regiospecifically carbon atom 14 of (S)- -N- methyltetrahydroprotoberberines has been discovered in a number of plant cell cultures originating from species containing protopine alkaloids; the monooxygenase was solubilized, partially purified (100-fold) and characterized.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie