Retrospective analysis of circulatory support with the Impella CP (R) device in patients with therapy refractory cardiogenic shock

Lackermair, K.; Sattler, S.; Huber, B. C.; Grabmaier, U.; Weckbach, L. T.; Bauer, A.; Theiss, H. D.; Hausleiter, J.; Mehilli, J.; Massberg, S. und Brunner, S. (2016): Retrospective analysis of circulatory support with the Impella CP (R) device in patients with therapy refractory cardiogenic shock. In: International Journal of Cardiology, Bd. 219: S. 200-203

Abstract

Background: In cardiogenic shock (CS) the Impella CP (R) device provides a fast available left ventricular circulatory support of up to 4.0 L/min. However, the use of the Impella CP (R) device was not systematically analysed yet. Methods: We performed a retrospective analysis of 28 consecutive patients suffering from severe therapy refractory CS treated with Impella CP (R). Mortality was estimated using the SAPS II-Score. Primary outcome was 30-day survival. We compared the different aetiologies of CS and the effect of additional extracorporeal life support (ECLS). Results: Aetiology of CS was acute coronary syndrome (ACS) in 15 patients, 9 patients received additional therapy with ECLS. SAPS II was 73 +/- 14, representing an estimated mortality of 87.1%. 18 patients deceased representing a 30-day survival of 36%. Comparing the different aetiologies, ACS-CS patients show a trend towards better survival. Additional therapy with ECLS did not change 30-day survival. In 3 cases, vascular complication needing surgical treatment occurred. All other patients showed no relevant complications except for the commonly seen haemolysis with consecutive need of transfusion. Conclusion: Our data could demonstrate that the Impella CP (R) application in these severely diseased patients is feasible and safe. Compared to the estimated mortality, the 30-day survival seems to be improved. (C) 2016 ELSEVIER. All rights reserved.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0167-5273
• Sprache: Englisch