Population-Based Imaging and Radiomics: Rationale and Perspective of the German National Cohort MRI Study

Schlett, C. L.; Hendel, T.; Weckbach, S.; Reiser, M.; Kauczor, H. U.; Nikolaou, K.; Günther, M.; Forsting, M.; Hosten, N.; Völzke, H. und Bamberg, F. (2016): Population-Based Imaging and Radiomics: Rationale and Perspective of the German National Cohort MRI Study. In: Röfo : fortschritte Auf Dem Gebiet Der Röntgenstrahlen und Der Bildgebenden Verfahren, Bd. 188, Nr. 7: S. 652-661

Abstract

The MRI study within the German National Cohort, a large-scale, population-based, longitudinal study in Germany, comprises comprehensive characterization and phenotyping of a total of 30 000 participants using 3-Tesla whole-body MR imaging. A multi-centric study design was established together with dedicated core facilities for e.g. managing incidental findings or providing quality assurance. As such, the study represents a unique opportunity to substantially impact imaging-based risk stratification leading to personalized and precision medicine. Supported by the developments in the field of computational science, the newly developing scientific field of radiomics has large potential for the future. In the present article we provide an overview on population-based imaging and Radiomics and conceptualize the rationale and design of the MRI study within the German National Cohort.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1438-9029
• Sprache: Englisch