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Anders, Hans-Joachim; Kretzler, Matthias (2016): Personalized immunomonitoring in lupus and lupus nephritis. In: Nature Reviews Nephrology, Vol. 12, No. 6: pp. 320-321
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The heterogeneity of pathomechanisms leading to systemic lupus erythematosus (SLE) might contribute to between-patient variations in treatment response. A new, longitudinal transcriptome analysis has identified molecularly distinct subgroups of SLE that correlate with disease activity;use of such disease classifiers might facilitate the development of stratified treatment recommendations.