Cathepsins are potential therapeutic targets in kidney disease

Kumar, Santhosh V. R. und Anders, Hans-Joachim (2016): Cathepsins are potential therapeutic targets in kidney disease. In: Kidney international, Bd. 90, Nr. 5: S. 933-935

Abstract

Cathepsins are a class of proteases with diverse biological activities inside and, in part, also outside cells. Recent studies suggest that cathepsins are involved in the pathogenesis of diabetic nephropathy and in disease activity of autoimmune immune complex glomerulonephritis. Targeting specific cathepsins with suitable antagonists may hold promises for therapeutic interventions.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0085-2538
• Sprache: Englisch