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Bidlingmaier, C.; Eberl, W.; Knöfler, R. und Kurnik, K. (2016): Präoperative Gerinnungsdiagnostik bei Kindern. In: Monatsschrift Kinderheilkunde, Bd. 164, Nr. 5: S. 407-417

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Abstract

Each year approximately 500,000 pediatric inpatient operations, mostly elective, are carried out in Germany. Bleeding events are a feared and sometimes fatal complication. Laboratory analytical screening tests have been shown to be ineffective for identification of children particularly at risk;therefore, greater emphasis is now placed on medical history taking. If a coagulopathy is suspected extended diagnostics must be carried out to exclude the most common bleeding disorder, von Willebrand disease. Factor XIII deficiency and platelet function defects must also be considered. As bleeding cannot be ruled out even after extensive laboratory examinations, surgeons, pediatricians involved in aftercare and parents must be aware of the risk of hemorrhage. Surgery has to be clearly necessary and an emergency plan must be available in the event of bleeding. Preoperative laboratory screening for thrombophilic risk -factors is not generally recommended. In contrast to adults, a perioperative thrombosis prophylaxis is rarely necessary.

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