Carbon nano onions cross the blood brain barrier

Pakhira, Bholanath; Ghosh, Mitrajit; Allam, Afreen und Sarkar, Sabyasachi (2016): Carbon nano onions cross the blood brain barrier. In: Rsc Advances, Bd. 6, Nr. 35: S. 29779-29782

Abstract

We show the crossing of small sized water soluble fluorescent carbon nano onion (wsCNO) through the blood brain barrier (BBB) in the Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) murine model as well as in glioblastoma multiforme (GBM) induced mice. It is readily excreted from the body after a few days suggesting its possible use as cargo in drug delivery.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 2046-2069
• Sprache: Englisch