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Pakhira, Bholanath; Ghosh, Mitrajit; Allam, Afreen and Sarkar, Sabyasachi (2016): Carbon nano onions cross the blood brain barrier. In: Rsc Advances, Vol. 6, No. 35: pp. 29779-29782

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Abstract

We show the crossing of small sized water soluble fluorescent carbon nano onion (wsCNO) through the blood brain barrier (BBB) in the Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) murine model as well as in glioblastoma multiforme (GBM) induced mice. It is readily excreted from the body after a few days suggesting its possible use as cargo in drug delivery.

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