Labial Salivary Glands in Infants: Histochemical Analysis of Cytoskeletal and Antimicrobial Proteins

Stoeckelhuber, Mechthild; Loeffelbein, Denys J.; Olzowy, Bernhard; Schmitz, Christoph; Koerdt, Steffen and Kesting, Marco R. (2016): Labial Salivary Glands in Infants: Histochemical Analysis of Cytoskeletal and Antimicrobial Proteins. In: Journal of Histochemistry & Cytochemistry, Vol. 64, No. 8: pp. 502-510

Abstract

Human labial glands secrete mucous and serous substances for maintaining oral health. The normal microbial flora of the oral cavity is regulated by the acquired and innate immune systems. The localization and distribution of proteins of the innate immune system were investigated in serous acinar cells and the ductal system by the method of immunohistochemistry. Numerous antimicrobial proteins could be detected in the labial glands: -defensin-1, -2, -3;lysozyme;lactoferrin;and cathelicidin. Cytoskeletal components such as actin, myosin II, cytokeratins 7 and 19, - and -tubulin were predominantly observed in apical cell regions and may be involved in secretory activities.

• Item Type: Journal article
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 0022-1554
• Alliance/National Licence: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
• Language: English