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Jakob, A. (2016): Kawasaki-Syndrom. In: Monatsschrift Kinderheilkunde, Vol. 164, No. 3: pp. 241-253

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The Kawasaki disease is one of the last pediatric diseases whose precise etiology is still unclear at probably infectiological genesis. A genetic predisposition exists, as the incidence varies depending on ethnicity. The clinical picture is well described, but the similarity to other diseases and lack of "classic criteria", so-called "Incomplete Kawasaki disease" complicate the diagnosis. Other symptoms, certain laboratory constellations and echocardiography can help to initiate timely therapy and thereover reduce the cardiac involvement. Intravenous immunoglobulins have a proven effect in this regard. Alternatives, especially for refractory cases are available. In the acute stage, the cardiac involvemnet may present as pancarditis. The long-term morbidity though is determined by the development of coronary aneurysms. With increasing aneurysms decreases the trend of regression and increases the risk of thrombosis and development of stenosis. Therefore lifelong cardiological long-term follow-up may sometimes be necessary.

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