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Schlichthaerle, Thomas; Strauss, Maximilian T.; Schueder, Florian; Woehrstein, Johannes B. and Jungmann, Ralf (2016): DNA nanotechnology and fluorescence applications. In: Current Opinion in Biotechnology, Vol. 39: pp. 41-47

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Structural DNA nanotechnology allow researchers to use the unique molecular recognition properties of DNA strands to construct nanoscale objects with almost arbitrary complexity in two and three dimensions. Abstracted as molecular breadboards, DNA nanostructures enable nanometer-precise placement of guest molecules such as proteins, fluorophores, or nanoparticles. These assemblies can be used to study biological phenomena with unprecedented control over number, spacing, and molecular identity. Here, we give a general introduction to structural DNA nanotechnology and more specifically discuss applications of DNA nanostructures in the field of fluorescence and plasmonics.

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