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Parodi, Katia (2016): Unconventional Imaging in Ion Beam Therapy: Status and Perspectives. In: Acta Physica Polonica B, Vol. 47, No. 2: pp. 447-452

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Owing to their favorable physics interaction properties, ion beams can offer unprecedented ballistic accuracy for highly conformal irradiation of complex-shaped tumour volumes, with excellent sparing of surrounding healthy tissue and critical organs. However, these advantageous dosimetric properties also bear enhanced sensitivity to uncertainties in treatment planning and delivery, calling for an increasing need of advanced imaging to ensure safe application of the intended dose to the targeted area during the entire course of fractionated therapy. Although it is common perception that in-room image-guidance of particle therapy is still lagging behind modern integrated solutions of photon therapy, new technological developments are being pursued by several groups to exploit the unique features of ion beam interaction in matter for innovative image-guidance concepts, with particular focus on in vivo verification of the ion beam range.

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