Cobalt-Catalyzed C(sp(2))-C(sp(3)) Cross-Coupling Reactions of Diarylmanganese Reagents with Secondary Alkyl Iodides

Hofmayer, Maximilian S.; Hammann, Jeffrey M.; Haas, Diana und Knochel, Paul (2016): Cobalt-Catalyzed C(sp(2))-C(sp(3)) Cross-Coupling Reactions of Diarylmanganese Reagents with Secondary Alkyl Iodides. In: Organic Letters, Bd. 18, Nr. 24: S. 6456-6459

Abstract

A cobalt-catalyzed cross-coupling of diarylmanganese reagents with secondary alkyl iodides using the THF-soluble salt CoCl2. 2LiCl, which leads to the cross-coupling products in up to 92% yield, is reported. High diastereoselectivities can be reached in these cross-couplings (dr up to 99:1). Remarkably, rearrangement of secondary alkyl iodides to unbranched products was not observed in these C-C forming reactions.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Chemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1523-7060
• Sprache: Englisch