Preparation of Functionalized 2,7-Naphthyridines by Directed Lithiation with (2,2,6,6-Tetramethylpiperidyl)lithium and Their Regioselective Iron-Catalyzed Cross Couplings

Greiner, Robert; Blanc, Romain; Petermayer, Christian; Karaghiosoff, Konstantin and Knochel, Paul (2016): Preparation of Functionalized 2,7-Naphthyridines by Directed Lithiation with (2,2,6,6-Tetramethylpiperidyl)lithium and Their Regioselective Iron-Catalyzed Cross Couplings. In: Synlett, Vol. 27, No. 2: pp. 231-236

Abstract

We report the regioselective functionalization of 2,7-naphthyridines by using (2,2,6,6-tetramethylpiperidyl)lithium as a base, together with the regioselective iron-catalyzed cross-coupling reactions of the products to give tetraalkylated 2,7-naphthyridines selectively.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 0936-5214
• Language: English