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Greiner, Robert; Blanc, Romain; Petermayer, Christian; Karaghiosoff, Konstantin; Knochel, Paul (2016): Preparation of Functionalized 2,7-Naphthyridines by Directed Lithiation with (2,2,6,6-Tetramethylpiperidyl)lithium and Their Regioselective Iron-Catalyzed Cross Couplings. In: Synlett, Vol. 27, No. 2: pp. 231-236
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Abstract

We report the regioselective functionalization of 2,7-naphthyridines by using (2,2,6,6-tetramethylpiperidyl)lithium as a base, together with the regioselective iron-catalyzed cross-coupling reactions of the products to give tetraalkylated 2,7-naphthyridines selectively.