Mild Cobalt-Catalyzed Negishi Cross-Couplings of (Hetero)arylzinc Reagents with (Hetero)aryl Halides

Haas, Diana; Hammann, Jeffrey M.; Lutter, Ferdinand H. und Knochel, Paul (2016): Mild Cobalt-Catalyzed Negishi Cross-Couplings of (Hetero)arylzinc Reagents with (Hetero)aryl Halides. In: Angewandte Chemie-international Edition, Bd. 55, Nr. 11: S. 3809-3812

Abstract

A catalytic system consisting of CoCl(2)2LiCl (5mol%) and HCO2Na (50mol%) enables the cross-coupling of various N-heterocyclic chlorides and bromides as well as aromatic halogenated ketones with various electron-rich and -poor arylzinc reagents. The reactions reached full conversion within a few hours at 25 degrees C.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Chemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1433-7851
• Sprache: Englisch