A DPOAE assessment of outer hair cell integrity in ears with age-related hearing loss

Überfuhr, Margarete Anna; Fehlberg, Hannah; Goodman, Shawn S. und Withnell, Robert H. (2016): A DPOAE assessment of outer hair cell integrity in ears with age-related hearing loss. In: Hearing Research, Bd. 332: S. 137-150

Abstract

Distortion product otoacoustic emissions (DPOAEs) were used to assess outer hair cell (OHC) integrity in human ears with age-related hearing loss. Sound pressure measurements were made in the ear canal over the stimulus range 40-90 dB SPL (L-2), with L-1 = 0A5*L-2 + 44 with F-2 = 2 and 3 or 4 kHz. Model generated DPOAE I/O functions were fit to DPOAE data to quantify the contribution of loss of nonlinearity (OHC loss) to the hearing loss. Results suggest OHC loss as a contributing cause of age-related hearing, regardless of audiogram configuration. It seems likely that OHC and stria] pathology co-exist in ears with AHL. (C) 2015 Elsevier B.V. All rights reserved.

• Dokumententyp: Zeitschriftenartikel
• Fakultätsübergreifende Einrichtungen: Graduate School of Systemic Neurosciences (GSN)
• Themengebiete: 500 Naturwissenschaften und Mathematik > 500 Naturwissenschaften
• ISSN: 0378-5955
• Sprache: Englisch