2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

Simon, Thorsten; Hero, Barbara; Schulte, Johannes H.; Deubzer, Hedwig; Hundsdoerfer, Patrick; Schweinitz, Dietrich von; Fuchs, Jörg; Schmidt, Matthias; Prasad, Vikas; Krug, Barbara; Timmermann, Beate; Leuschner, Ivo; Fischer, Matthias; Langer, Thorsten; Astrahantseff, Kathy; Berthold, Frank; Lode, Holger und Eggert, Angelika (2017): 2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors. In: Klinische Pädiatrie, Bd. 229, Nr. 3: S. 147-167

Abstract

The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0300-8630
• Sprache: Englisch