| Stentzel, Sebastian; Hagl, Beate; Abel, Felicitas; Kahl, Barbara C.; Rack-Hoch, Anita; Bröker, Barbara M.; Renner, Ellen D. (2017): Reduced Immunoglobulin (Ig) G Response to Staphylococcus aureus in STAT3 Hyper-IgE Syndrome. In: Clinical infectious Diseases, Vol. 64, No. 9: pp. 1279-1282 |
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Abstract
STAT3 hyper-IgE syndrome (STAT3-HIES) patients presented with significantly lower Staphylococcus aureus-specific serum IgG compared to cystic fibrosis patients despite recurrent S. aureus infections. Immunoglobulin replacement therapy increased S. aureus-specific IgG in STAT3-HIES patients and attenuated the clinical course of disease suggesting a role of humoral immunity in S. aureus clearance.
| Item Type: | Journal article |
|---|---|
| Faculties: | Medicine |
| Subjects: | 600 Technology > 610 Medicine and health |
| ISSN: | 1058-4838 |
| Language: | English |
| ID Code: | 50401 |
| Deposited On: | 14. Jun 2018 09:43 |
| Last Modified: | 14. Jun 2018 09:43 |
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