Low-level Mercury Exposure and Risk of Asthma in School-age Children

Heinrich, Joachim; Guo, Feng und Trepka, Mary Jo (2017): Low-level Mercury Exposure and Risk of Asthma in School-age Children. In: Epidemiology, Bd. 28, Nr. 1: S. 116-118

Abstract

Background: Although mercury exposure has been associated with several adverse health effects, the association with childhood asthma is under investigated. Therefore, we explore the association between mercury and childhood asthma in a population with low mercury levels. Methods: Mercury levels were measured in blood and urine in 1,056 children ages 5-14 years. In addition to including questions about asthma diagnosis and wheezing, the study measured bronchial hyperresponsiveness and allergic sensitization to common aeroallergens. Logistic regression analysis adjusted for major potential confounders. Results: Overall the adjusted odds ratios (aOR) between log blood mercury and the outcomes were 0.8 (95% CI: 0.63, 1.11) for asthma, 0.9 (95% CI: 0.79, 1.14) for wheeze, 1.1 (95% CI: 0.60, 2.03) for bronchial hyperresponsiveness, and 1.0 (95% CI: 0.80, 1.17) for allergic sensitization. Urine mercury adjusted for creatinine was also not associated with any of these allergy-related outcomes. Conclusions: While the results did not support an association between mercury exposure and asthma, studies are needed to assess prenatal and lifetime exposure to mercury and asthma.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1044-3983
• Allianz-/Nationallizenz: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
• Sprache: Englisch