Risk factors for lymph node metastases of facial cutaneous squamous cell carcinoma

Obermeier, Katharina; Tröltzsch, Matthias; Ehrenfeld, Michael und Smolka, Wenko (2017): Risk factors for lymph node metastases of facial cutaneous squamous cell carcinoma. In: Journal of Cranio-Maxillofacial Surgery, Bd. 45, Nr. 8: S. 1138-1142

Abstract

Purpose: Determining the risk factors for lymph node metastases of facial cutaneous squamous cell carcinoma and identifying their value for predicting nodal spread. Material and methods: Data on 99 patients were examined retrospectively. Conditions such as tumor staging, tumor thickness, location, histological grading, R1-resection, local recurrence, lymph node metastases, and neurovascular and lymphovascular invasion were evaluated. Statistical analysis was performed using a logistic regression analysis and Fisher's test. Results: Logistic regression analysis indicates that poor differentiation, R1-resection, and periorbital location are high risk factors for nodal spread in facial cutaneous squamous cell carcinoma. Conclusion: Patients who show poorly differentiated facial cutaneous squamous cell carcinoma and/or have had previous R1-resection might benefit from treatment of regional lymph nodes. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1010-5182
• Sprache: Englisch