Abstract
AimThis cross-sectional study was repeated at two time points and investigated the influence of gingivitis, smoking and body mass index (BMI) on the systemic inflammatory markers high-sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL6) in 10- and 15-year-olds. Materials and MethodsThe study sample of two birth cohorts, i.e. GINIplus and LISAplus, from the Munich centre consisted of 806 and 846 subjects who were evaluated at 10- and 15-year follow-ups respectively. Children and their parents completed questionnaires on participant-related lifestyle information. Gingivitis was measured at the sextant level using a simplified sulcus-bleeding index. Serum hs-CRP and IL6 levels were obtained from blood samples. Multiple logistic regressions adjusting for lifestyle-related factors and other confounders were performed to assess associations between the specified variables. ResultsThere were no associations between gingivitis and the inflammatory markers hs-CRP and IL6 in 10-year-olds. In 15-year-olds, gingivitis (aOR: 2.17;95% CI: 1.25-3.77);daily smoking (aOR: 6.27;95% CI: 1.39-28.39);and being overweight/obese (aOR: 4.95;95% CI: 0.73-33.68) were identified as significantly influencing factors for elevated hs-CRP values. Oral hygiene did not influence hs-CRP. ConclusionIn this study, hs-CRP was positively associated with gingivitis, smoking daily and overweight/obesity among 15-year-olds.
Dokumententyp: | Zeitschriftenartikel |
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Fakultät: | Medizin > Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin |
Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
ISSN: | 0303-6979 |
Sprache: | Englisch |
Dokumenten ID: | 51013 |
Datum der Veröffentlichung auf Open Access LMU: | 14. Jun. 2018, 09:44 |
Letzte Änderungen: | 23. Jul. 2024, 10:21 |