Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Fabisiak, Adam; Wlodarczyk, Jakub; Fabisiak, Natalia; Storr, Martin und Fichna, Jakub (2017): Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal. In: Journal of Neurogastroenterology and Motility, Bd. 23, Nr. 3: S. 341-348

Abstract

Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for agents targeting histamine receptors as a potential therapeutic option in clinical treatment. In this review, the role of histamine and histamine receptors is debated. Moreover, the clinical evidence of anti-histamine therapeutics in irritable bowel syndrome is discussed.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 2093-0879
• Sprache: Englisch