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Fendler, Wolfgang P.; Rahbar, Kambiz; Herrmann, Ken; Kratochwil, Clemens and Eiber, Matthias (2017): Lu-177-PSMA Radioligand Therapy for Prostate Cancer. In: Journal of Nuclear Medicine, Vol. 58, No. 8: pp. 1196-1200

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Abstract

Lu-177-prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) using inhibitors of PSMA is a novel therapeutic option in patients withmetastatic castration-resistant prostate cancer. The current literature suggests that this therapy is well tolerated and effective. On the basis of clinical need and current evidence, the therapy is being implemented in a growing number of centers worldwide. Here, we review important aspects of Lu-177-PSMA RLT, including patient stratification, the therapy protocol, concomitant medication, and follow-up, to inform medical staff involved in the RLT and care of patients with metastatic castration-resistant prostate cancer.

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