Efficient Descriptor-Based Segmentation of Parotid Glands With Nonlocal Means

Wachinger, Christian; Brennan, Matthew; Sharp, Greg C. and Golland, Polina (2017): Efficient Descriptor-Based Segmentation of Parotid Glands With Nonlocal Means. In: Ieee Transactions On Biomedical Engineering, Vol. 64, No. 7: pp. 1492-1502

Abstract

Objective: We introduce descriptor-based segmentation that extends existing patch-based methods by combining intensities, features, and location information. Since it is unclear which image features are best suited for patch selection, we perform a broad empirical study on a multitude of different features. Methods: We extend nonlocal means segmentation by including image features and location information. We search larger windows with an efficient nearest neighbor search based on kd-trees. We compare a large number of image features. Results: The best results were obtained for entropy image features, which have not yet been used for patch-based segmentation. We further show that searching larger image regions with an approximate nearest neighbor search and location information yields a significant improvement over the bounded nearest neighbor search traditionally employed in patch-based segmentation methods. Conclusion: Features and location information significantly increase the segmentation accuracy. The best features highlight boundaries in the image. Significance: Our detailed analysis of several aspects of nonlocal means-based segmentation yields new insights about patch and neighborhood sizes together with the inclusion of location information. The presented approach advances the state-of-the-art in the segmentation of parotid glands for radiation therapy planning.

• Item Type: Journal article
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 0018-9294
• Language: English