An accurate model for the computation of the dose of protons in water

Embriaco, A.; Bellinzona, V. E.; Fontana, A. und Rotondi, A. (2017): An accurate model for the computation of the dose of protons in water. In: Physica Medica-European Journal of Medical Physics, Bd. 38: S. 66-75

Abstract

Purpose: The accurate and fast calculation of the dose in proton radiation therapy is an essential ingredient for successful treatments. We propose a novel approach with a minimal number of parameters. Methods: The approach is based on the exact calculation of the electromagnetic part of the interaction, namely the Moliere theory of the multiple Coulomb scattering for the transversal 1D projection and the Bethe-Bloch formula for the longitudinal stopping power profile, including a gaussian energy straggling. To this e.m. contribution the nuclear proton-nucleus interaction is added with a simple two-parameter model. Then, the non gaussian lateral profile is used to calculate the radial dose distribution with a method that assumes the cylindrical symmetry of the distribution. Results: The results, obtained with a fast C++ based computational code called MONET (MOdel of ioN dosE for Therapy), are in very good agreement with the FLUKA MC code, within a few percent in the worst case. Conclusions: This study provides a new tool for fast dose calculation or verification, possibly for clinical use. (C) 2017 Associazione Italiana di Fisica Medica.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Physik
• Themengebiete: 500 Naturwissenschaften und Mathematik > 530 Physik
• ISSN: 1120-1797
• Sprache: Englisch