Methods for the Synthesis of Substituted Azetines

Baumann, Andreas N.; Eisold, Michael; Music, Arif; Haas, Geoffrey; Kiw, Yu Min und Didier, Dorian (2017): Methods for the Synthesis of Substituted Azetines. In: Organic Letters, Bd. 19, Nr. 20: S. 5681-5684

Abstract

Spurred on by the recent emerging interest from the chemical community for unsaturated four-membered heterocycles, an unprecedented approach to nitrogen-containing four-membered rings has been designed. 3,4-Disubstituted 2-azetines were synthesized from commercially available substrates, allowing for a straightforWard access to a new library of chiral functionalized azetidines and amino alcohols. This original approach was applied to efficiently prepare functionalized azobenzenes, an emerging class of molecules with a large potential in photopharmacology.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Chemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1523-7060
• Sprache: Englisch