Abstract
Space is represented in the mammalian brain by the activity of hippocampal place cells, as well as in their spike-timing correlations. Here, we propose a theory for how this temporal code is transformed to spatial firing rate patterns via spike-timing-dependent synaptic plasticity. The resulting dynamics of synaptic weights resembles well-known pattern formation models in which a lateral inhibition mechanism gives rise to a Turing instability. We identify parameter regimes in which hexagonal firing patterns develop as they have been found in medial entorhinal cortex.
Dokumententyp: | Zeitschriftenartikel |
---|---|
Fakultät: | Biologie > Department Biologie II > Neurobiologie |
Fakultätsübergreifende Einrichtungen: | Graduate School of Systemic Neurosciences (GSN) |
Themengebiete: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften; Biologie
500 Naturwissenschaften und Mathematik > 500 Naturwissenschaften |
ISSN: | 0031-9007 |
Sprache: | Englisch |
Dokumenten ID: | 54650 |
Datum der Veröffentlichung auf Open Access LMU: | 14. Jun. 2018, 09:56 |
Letzte Änderungen: | 04. Nov. 2020, 13:34 |